Precisely as Ruben Amorim probably assumed his luck wasn't changing, Manchester United managed to inflict the home side's first home defeat in domestic football since February.
The Austrian coach's players started strongly rightfully went ahead by way of Jean-Philippe Mateta's repeated spot-kick. But they could not to capitalize on their control and having failed to find the net at Selhurst, Amorim's team countered twice in nine minutes via their summer signing and Mason Mount.
This represented a difficult day concluding of a long week for the home manager, who saw his winger depart hurt with a concerning injury in the first period.
His Portuguese counterpart probably contained his reactions subdued as he headed off the pitch directly following the match's conclusion.
Amorim had played down similarities regarding both managers' strategic methods ahead of the match, while admitting that Palace "simply perform things better than us|aspects superior to ours|elements more effectively".
The reaction following the poor performance versus reduced Everton was to change both wing-backs, including the young winger shifting to the right side while the Portuguese assumed Dorgu's position.
United must have sensed a opening to capitalize since they possessed additional preparation time and came close to leading inside the opening minute.
A long throw caused chaos inside Palace's defense yet remarkably the ex-United shot-stopper produced a point-blank save on his goalline to deny Casemiro.
The close shave acted as an alert for the home team post the lunchtime beginning that was scheduled by TV requirements.
Quickly opportunities began to come frequently. Following wasted numerous attempts during European action, it looked perhaps it wouldn't be the striker's opportunity when he twice dragged efforts missing the goal inside the opening 15 minutes.
But in a week when talks over Mateta's contract extension have stalled, the French striker emerged who opened the scoring.
One more perfect ball from the England international drew the defender into the challenge after recently producing superb interception to prevent the Spaniard, Yoro could only bring down his compatriot within the 18-yard area.
Palace's shot-stopper came out in a baseball cap to shield his eyes from the glare yet he'll feel regret for permitting the visitors to draw equal after the restart.
Palace were caught napping from a rapid Fernandes set-piece allowing the forward to bring under control and pivot in one motion to generate a strike that sailed into the far corner.
Following weathering a chaotic situation where Zirkzee almost scored again at the wrong end, their afternoon got even better a few minutes later as the Dutch attacker was brought down near the 18-yard line by the English center-back.
A temporary uncertainty developed in the defensive wall as the captain passed the free-kick to Mount and that allowed him to defeat the goalkeeper using a fierce strike.
Without Sarr's pace to call on, the home team struggled to create additional opportunities while the visitors managed to complete an important win that means Manchester United leapfrog the Eagles up to sixth spot.